15 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease associated ... association • M > F Clinical ... (Clinical Dx). ... Arthritis, AS Treatment ... #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Associated with: ... Ocular- 50%: Ptosis ... Bedside: ice pack test ... /Edrophonium test ... Gravis #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... experience Statin-Associated ... IU/I • SAMS clinical ... • If statin-associated ... myopathy #diagnosis #management
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
Staphylococcus-associated ... Summary CLINICAL ... • Nephritic syndrome ... • No serologic tests ... deposits common TREATMENT
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Necrotizing, pauci-immune ... respiratory tracts Immune ... • Cogan Syndrome ... lesions-interstitial keratitis, uveitis ... retinopathy Lab Tests
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... underlying genetic immune ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology: • Immune ... Guillain-Barre Clinical ... GQ1b IgG Antibody associated ... #diagnosis #management ... #treatment #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... skin lesions, ocular ... recovery uveitis ... Other Pathogens Associated ... Differential #Diagnosis #Management
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... impaired cellular immune ... HIV/AIDS, CGD) Clinical ... Penicillium • BDG is associated ... #treatment #fungal
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... and sensitive tests ... and cauda equina TREATMENT ... #diagnosis #management