16 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Angioedema: • Mast ... cell-mediated in > 90% of cases ... is key • Mast ... #Angioedema #Classification
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Allergic reaction ... allergen's surface as ... activate macrophages, mast ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... macrophages, HLA class ... Tissue edema #Allergic ... Rhinitis #Rhinorrhea #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... reactions #types #allergy ... #table #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
allergens and activate mast ... leading to an allergic ... cell surfaces causes ... causes development ... #Types #Classification
Some H1 antihistaminic Drugs in Clinical Use
1st Generation Antihistamines:
Ethanolamjnes - Carbinoxamine (Clistin), Dimenhydrinate (salt of diphenhydramine)(Dramamine),
Clinical Use 1st ... Fexofenadine (Allegra ... antihistamines #classification ... #Pharmacology #classes
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... • MOA: Block fast ... Weak Blockade, Fast ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... • MOA: Block fast ... Weak Blockade, Fast ... #Pharmacology #Classification ... #Classes #pathophysiology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
functional status - Able ... metabolic equivalent able ... ASA class If ... event, follow ACC algorithm ... Stable patients