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Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Statins), ETOH Infection ... Dermatomyositis) AKI ... Cast formation: ... hyperkalemia or ATN
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Statins - ETOH - Infection ... Cast formation: ... hyperkalemia or ATN
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... Light chain (LC) cast ... Cisplatin • ATN ... Kidney #Injury #AKI ... Cancer #Oncology #Differential
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Acellular Casts ... • Hyaline Casts ... tubular necrosis (ATN ... can be either infectious ... or non-infectious
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
) - Differential ... Epithelial cell casts ... Obstruction • Cast ... allopurinol, PPI) • Infections ... KidneyInjury #Nephrology #Differential
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... ) - Differential ... C3/C4, Other • ATN ... AIN: Medication, Infection ... Medicine @SCVMCMed #AKI
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential ... Post-infectious ... Injury/Necrosis (ATN ... • Toxins • Infection
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Kidney Injury - Differential ... white blood cell casts ... or pigmented casts ... Kidney #Injury #AKI ... #Differential #
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Kidney Injury (AKI ... Liano 1996) - ATN ... disease — 21% - AKI ... CKD— 13% (mostly ATN ... Algorithm #Causes #Differential
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Kidney Injury - Differential ... : • Tubules (ATN ... drtonydang @CMC_IM #AKI ... KidneyInjury #Causes #Differential