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diagnosis differential classification signs symptoms behcet cryoglobulinemia cryoglobulins dermatology disease henochscholeinpurpura hsp iga management pathophysiology skin types vasculitides
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Primary: 50% Cutaneous ... : • Immune Complex ... Ig A (HSP) - ... Disease • Cogan syndrome ... #dermatology #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... - GI tract: abdominal ... strong sign of cutaneous ... Supply gut -> abdominal ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... causing endothelial injury ... HBV infection, HIV ... Henoch-Schönlein purpura) • Cutaneous ... classification #rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
adhesion of IgA complexes ... response) - Cutaneous ... 85%) - Colicky abdominal ... nephrotic/nephritic syndrome ... and ankles) #HSP
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
of shoulder and hip ... multiplex • GI tract: Abdominal ... pauci-immune GN Immune Complex ... gut involvement, abdominal ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... ) • Cutaneous Lesions ... to local skin injury ... • Nonsurgical abdominal ... signs #symptoms #rheumatology
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