18 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Highest • Bone • Liver ... Most common symptoms ... Primary biliary Cholangitis ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... PBC Signs and Symptoms ... obstruction • ALP ... or higher • Liver ... #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... suspicious clinical symptoms ... Areas of diagnostic ... ALP, alkaline phosphatase ... #Algorithm #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... Care focuses on symptom ... control, judicious ... #diagnosis #management ... #summary #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... mineralization Symptoms ... respiratory failure • Neurologic ... fractures • Dental ... Hyophosphatasia #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... - Symptoms of ... hepatocellular pattern of liver ... upper limit of normal ... #Management #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... suspected HH based on symptoms ... <45% and SF is normal ... hemochromatosis #algorithm #diagnosis ... #management #hepatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... splenomegaly, abnormal ... neurology, back ... pain Haematology ... Peds #Pediatrics #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
the spleen or liver ... translocation • Types: Classification ... also arise in normal ... Differential Diagnosis ... Malignancies (eg CML, ALL
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... : INR/PT, aPTT(liver ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... not required in all