3 results
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Sclerotic bone changes ... Rule out other causes ... Nonspecific inflammatory changes ... antiinflammatory properties e.g ... , IL-17 inhibitors
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... tinnitus, visual changes ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
Causes of ST Segment ... STE: "Pardee's sign ... dissection • Sodium-channel ... diagnosis #cardiology #ecg ... #ekg #electrocardiogram