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diagnosis differential lfts causes ascites injury albumin abnormal chemistry elevated hepatocellular hepatomegaly hypertension interpretation liverenzymes liverfunctiontests patterns portal rvalue serum
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
ascites albumin gradient ... protein ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... #hepatology #differential ... #diagnosis #algorithm
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... cirrhosis, Portal ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
(SAAG) - Differential ... >1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... - Acute fatty liver ... Differential #Diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... for Transaminitis ... Congenital, Others, Cirrhosis ... #hepatology #LiverFunctionTests
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Cirrhosis ... - Alcoholic hepatitis ... - Acute fatty liver ... #differential #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • NAFLD • Alcohol ... hepatitis • Drugs ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
) estimated by gradient ... HTN: ascites (SAAG ... /acute hepatitis ... sarcoidosis) • Liver ... Diagnosis #causes #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Drugs (MDMA), Alcohol ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #differential #Hepatology ... #transaminitis
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