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diagnosis differential causes injury hematology lfts management aclf chronic cirrhosis coagulation comparison deficiencies deficiency dili druginduced failure gap gastroenterology globulin
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... - Drug-Induced liver ... - Autoimmune ... disease - Hemochromatosis ... #Differential #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... Syndrome, Celiac Disease ... #algorithm #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Autoimmune ... #Causes #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... (AAH) Drug-Induced ... ) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Ischemia • Autoimmune ... • Drugs • AIH ... • Cholestatic disease ... • Alcoholic hepatitis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... from subclinical disease ... to acute liver ... #Hepatitis #AIH ... Diagnosis #Management #Hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis of Autoimmune ... ) or metabolic liver ... Possible drug-induced liver ... SMA >1:80 #Autoimmune ... #Hepatology #AIH
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Autoimmune: ... Autoimmune hepatitis ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ... dechallenge • Acute ... steatosis • Autoimmune ... #hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
) • Advanced Liver ... Disease - Alcohol ... , Viral hepatitis ... , Autoimmune • ... catastrophes, Acute
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