8 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
• Increased LDH ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Non-megaloblastic: Liver ... #MCV #Algorithm ... Diagnosis #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
) - Differential ... RBCs, muscle, liver ... anemia, PNH, immune ... metastatic melanoma • Solid ... Dehydrogenase #Elevated #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... muscle, kidneys • LDH ... #differential # ... #hepatology
General Approach to Anemia - Differential Diagnosis Framework
1) Check reticulocyte count to determine if hypo/hyper-proliferative
2) Exclude
hyper-proliferative 2) Exclude hemolysis ... hyper-proliferative (LDH ... haptoglobin) 3) Use MCV ... diagnosis #hematology ... #algorithm #reticulocyte
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... serologies, HCV ... muscle, Kidneys • LDH ... #diagnosis #differential ... #Hepatology #transaminitis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... Malignancies: Solid ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential