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diagnosis rheumatology differential vasculitis management acr2021 classification granulomatosis guidelines microscopic polyangiitis polychondritis progressive prs rapidly relapsing renal rpgn syndromes vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
(C-ANCA): GPA > ... >> MPA > eGPA • ... MPO-ANCA (P-ANCA ... ): eGPA, MPA >>> ... GPA Stanford Internal
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... Polyangiitis (MPA ... #Polyangiitis #GPA ... #Polyangiitis #MPA ... #Management #Treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
): GPA (granulomatous ... polyangiitis), MPA ... subglottic stenosis) in GPA ... , asthma (EGPA) ... diagnosis #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
capillaritis • EGPA ... > PR3 60% • GPA ... : - Aorta and ... LFT • ESR • ANA ... (Dx: GPA, EGPA,
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
< 30 years • Aorta ... Arteritis): • Aorta ... myeloperoxidase (MPO-ANCA ... progressive) EGPA ... > PR3 60/ GPA
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Large vessels (aorta ... • Lymphoma • GPA ... /EGPA • RA Diagnosis ... Nonspecific ↑ ESR, CRP, ANA ... affected tissue Treatment
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