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differential disease signs treatment aosd arteritis autoimmune behcet chronic classification cll erythematosus gca giantcell hematology hemeonc igg4 leukemia lupus lymphocytic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... 33% of healthy adults ... : The ANA patterns ... #Antibodies #ANA ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
aorta • Head ... autoantibodies (antinuclear ... antibodies, rheumatoid ... #management #phenotypes ... workup #treatment #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
common leukemia in adults ... lymphadenopathy and ... 3) Monoclonal antibodies ... #hemeonc #diagnosis ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• GCA: - Aorta ... Presentation - Systemic Symptoms ... LFT • ESR • ANA ... ) pattern: antibodies ... #rheumatology #
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... the chest/trunk Symptoms ... ANA Labs: • ↑ESR ... #rheumatology # ... management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... EGPA) • Auto-antibodies ... or serologies + symptoms ... • IF staining patterns ... #management #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... rheumatoid arthritis, adult-onset ... Induced Lupus: • Symptoms ... Serositis Labs: • ANA ... • (-) ANA + (+
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... meningitis), MCC CNS symptoms ... Glucocorticoids 5-ASA ... #management #signs ... #symptoms #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
cancer-associated adult ... • Anti-NXP2 (ANA ... (ANA present 80% ... pattern of muscle ... or head drop • ANA
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