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differential treatment ana arteritis autoimmune classification disease giantcell igg4 myopathy myositis phenotypes polychondritis prs pulmonary relapsing related renal syndromes temporal
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... : The ANA patterns ... #Antibodies #ANA ... #patterns #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Retroperitoneum and aorta ... autoantibodies (antinuclear ... antibodies, rheumatoid ... #management #phenotypes ... workup #treatment #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... them, but urgent rheumatology ... #Symptoms #Diagnosis ... #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and branches • GCA ... Presentation - Systemic Symptoms ... purpura: strong sign ... : antibodies directed ... #rheumatology #
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
ANCA vasculitis (AAV ... EGPA) • Auto-antibodies ... or serologies + symptoms ... • IF staining patterns ... #management #treatment
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... slow onset and pattern ... Myositis #Myopathy #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... Large vessels (aorta ... Anti-Matrilin-1 Ab ○ Antibodies ... Polychondritis #rheumatology ... #diagnosis #management
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