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management differential chronic leukemia lymphocytic lymphoma rheumatology workup classification dermatology hemeonc hemophagocytic hlh lymphohistiocytosis mds monoclonal myelodysplasia myelodysplastic nonhodgkins paraproteinemias
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... Reed Sternberg cell ... based on: - Cell ... type (B cell, T ... #oncology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
number of sites of disease ... Lymphoma Treatment ... #lymphoma #diagnosis ... classification #hematology ... #oncology #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... Transformation to large cell ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #hematology #hemeonc
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemopathies+++: Hodgkin ... , T-cell lymphoma ... , B-cell lymphoma ... • Autoimmune diseases ... #management #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... Myeloproliferative Disease ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Nephrogenic DI Hematologic ... Malignancy Risk: • Non-Hodgkins ... lymphoma • B cell ... lymphoma • Large B cell ... Adenocarcinoma Treatment
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... the mainstay of treatment ... hematopoietic stem cell ... #comparison #table ... #dermatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... MM, the plasma cell ... #Solitary #Cell ... #Hematology
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