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Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Pathogenesis and clinical ... bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... Complications: • Acute Asthma
Allergic Rhinitis Mild to severe persistent nasal mucosal inflammation to specific allergic triggers WHO? • 1 in
Birthday • Smoke / Allergen ... Associations: • Asthma ... Conjunctivitis Clinical
Asthma: immunopathogenesis. Allergens attach to, and are taken up by, dendritic cells that he the respiratory
Asthma: immunopathogenesis ... Allergens attach ... interaction of the allergen ... production allergic asthma ... #Asthma #immunopathogenesis
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... mediated; exposure to allergen ... development of allergen-specific ... Initial exposure to allergen ... recognize antigen on allergen's
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen
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 Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... cephalosporin), Food allergies ... Immunological Target: Allergen
Assessment of the Child with Chronic Asthma Are there other allergic disorders? - Allergic rhinitis - Eczema,
Child with Chronic Asthma ... - Allergens - animal ... Stress #Chronic #Asthma
Stepwise approach for managing asthma in youths greater than 12 years of age and adults as
approach for managing asthma ... of the National Asthma ... Allergen immunotherapy ... those with single allergies ... If asthma is well
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... Hay fever, Food allergies ... , Drug allergies ... , Eczema, Asthma
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... hay fever, food allergies ... , and drug allergies
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