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Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... Second Exposure to Allergen
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Initial exposure to allergen ... recognize antigen on allergen's ... Stevens-Johnson Syndrome
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... cephalosporin), Food allergies ... Immunological Target: Allergen ... Stevens-Johnson Syndrome
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen
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 Inpatient History & Physical (H&P) Presentation and Note Template • Chief Complaint/Concern • History of Present
Inpatient History ... • Past Medical History ... Medications • Allergies ... • Family History ... • Social History
Inpatient History & Physical (H&P) Presentation and Note Template, SOAP Note Template Chief Complaint, History of Present
Inpatient History ... , Past Medical History ... , Medications, Allergies ... , Family History ... , Social History
Asthma: immunopathogenesis. Allergens attach to, and are taken up by, dendritic cells that he the respiratory
Allergens attach ... interaction of the allergen ... degranulate when the allergens
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... hay fever, food allergies ... , and drug allergies
Outpatient History & Physical (H&P) Presentation and Note Template • Chief Complaint/Concern • History of Present
Outpatient History ... • Past Medical History ... Medications • Allergies ... • Family History ... • Social History
"I MD SOAPS" Infectious Diseases Exposure History I - Immunization - Vaccination status (age-appropriate, comorbidities, travel, etc) M
Diseases Exposure History ... drug exposure & allergies ... protection, past STI history ... Place - Travel history ... members, past ID history
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