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Allergic Rhinitis Mild to severe persistent nasal mucosal inflammation to specific allergic triggers WHO? • 1 in
Birthday • Smoke / Allergen ... Conjunctivitis Clinical ... Rhinitis #diagnosis #management
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Pathogenesis and clinical ... bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... mediated; exposure to allergen ... development of allergen-specific ... Initial exposure to allergen ... recognize antigen on allergen's
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen
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 Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... cephalosporin), Food allergies ... Immunological Target: Allergen
Asthma: immunopathogenesis. Allergens attach to, and are taken up by, dendritic cells that he the respiratory
Allergens attach ... interaction of the allergen ... degranulate when the allergens
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... hay fever, food allergies ... , and drug allergies
Assessment of the Child with Eczema Distribution of atopic eczema - The distribution of eczema tends to
Ingestion of an allergen ... an irritant or allergen ... food or other allergens ... condition and its management
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... Hay fever, Food allergies ... , Drug allergies
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
difficult airway - Allergies ... Change in clinical ... medical and surgical management
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