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diagnosis causes management algorithm chronic classification deficiency erythematosus fatigue gap gca giantcell globulin hodgkins iron lupus lymphoma monoclonal nutrition paraproteinemias
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
: Gl lesions / cancer ... hepcidin) • Others: Hemolysis ... Iron metabolism disorders ... Deficiency #Causes #differential ... #diagnosis #anemia
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... • Rheumatoid Arthritis ... Pulmonary Disease Neurologic ... • Somatization Disorder
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... leukemia • Lung cancer ... • Cervical cancer
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... • Coombs (-) hemolytic ... anemia due to cold ... #Monoclonal #Differential ... #Diagnosis #Oncology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... very remarkable w/differential ... systemic complaints- anemia ... Start steroids if concern ... them, but urgent rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Connective tissue disorders ... (RA, Temporal arteritis ... ovarian tumors, lung cancers ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
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