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diagnosis algorithm hematology management nutrition classification pathophysiology b12 laboratory mcv pressure pulse secondary vitamin abnormal approach arteritis ascorbicacid celiac cirrhosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... (specifically: iron ... deficiency, hemolysis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... malignancy • Iron ... deficiency anemia ... #Differential #
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... - Cobalamin Decreased ... Stomach: Pernicious anemia ... #Cobalamin #differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Microangiopathic Hemolytic Anemias ... • Early Iron ... Deficiency # ... Normocytic #Anemia
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... blood loss (Fe deficiency ... Diagnosis #causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Poisoning • Anemia ... Marrow Failure • Anemia ... Myelodysplasia #Anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia ... Diagnosis #Algorithm #Causes
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... Deficiency (Eg ... TlBC > 18% • Anemia ... #Microcytic #Anemia
Gastrointestinal Causes of Iron Deficiency Anemia • Mass lesions: Carcinoma, Large polyps • Inflammatory: Reflux esophagitis,
Gastrointestinal Causes ... of Iron Deficiency ... Anemia • Mass ... #Deficiency #Anemia ... #Causes #differential
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... Microcytic" • Iron ... thalassemia • Anemia ... morphologic #mcv #differential ... #diagnosis #causes
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