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diagnosis dermatology rheumatology management rash antimda5 antimda5dm antinxp2 antinxp2dm arteritis autoimmune clinical common distribution erythematosus gca giantcell lupus myopathy myositis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
the face, or the anterior ... ulcerations • Skin ... ulcerations • Auricular skin ... lesions: antihelix ... • Skin vasculopathies
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... heaped, wart-like lesions—Condyloma ... reddish brown spots ... resembling rashes caused ... Diagnosis #Clinical #Photo
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... lesions + Rheumatic ... involvement: May involve anterior ... chest wall, parts ... Rule out other causes
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
have typical DM skin ... the face, or the anterior ... ulcerations • Skin ... lesions: antihelix ... Muscle atrophy may cause
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
hyperkeratotic lesions ... honey-colored crusts ... Trunk, especially anterior ... ; pruritis #dermatology ... #rash #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... papulosquamous lesions ... permanent alopecia Differential ... Still disease, dermatomyositis ... Malignancy (e.g. hematologic
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... required due to skip ... lesions. ... identifies 85 to 95% of cases ... required +/- prompt ophthalmology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... ) • Anti-Mi2 (skin ... lesions) • Anti-TIF1 ... statins - probably caused ... #differential #
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