31 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... skeletal muscle and kidney ... Injury? ... Transaminitis #diagnosis #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... cardiac muscle, RBC, kidney ... cardiac muscle, kidneys ... #differential #
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
DILI and Type of Liver ... Injury #Medications ... #Differential # ... LiverInjury #Hepatology #Pharmacology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
injury < 26 weeks ... cardiac muscle, RBC, Kidney ... Cardiac muscle, Kidneys ... trimester placenta, kidneys ... chemistry #diagnosis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Circulation Failure Kidney ... Injury (DILI) ... Hepatitis Procedures Management ... gastroenterology #management
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... - Differential ... urinalysis, labs - Management ... appropriate) #Acute #Kidney ... #Injury #AKI #Differential
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Associated Acute Kidney ... Injury • Drug ... induced acute kidney ... Vancomycin #AKI #pharmacology ... toxicology #diagnosis #management
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... ) - 8g per liter ... removed • Acute kidney ... injury (≥ 1B) - ... #Indications #Management
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
causing Acute Kidney ... Injury (AKI) Prerenal ... #AKI #Acute #Kidney ... #Drugs #pharmacology ... #differential #
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... dose dependent injury ... #differential # ... Diagnosis #Management