20 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... NXP2, Mi-2, SAE Anti-Synthetase ... Syndrome: Jo-1, ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Tetanus, Transverse Myelitis ... heavy metals), Critical ... #differential #diagnosis
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology
Imaging Findings:
 • Os trigonum which has marrow
(Os Trigonum) Syndrome ... - MSK Radiology ... Case description ... #clinical #mri ... #diagnosis #msk
Haglund Syndrome - MSK Radiology
Imaging Findings:
 • The Haglund Deformity (enlarged superior margin calcaneal posterior process)
- MSK Radiology ... margin calcaneal posterior ... Case description ... #Heel #clinical ... #msk
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- Clinical Presentation ... bouts of HTN Diagnostic ... Diagnosis: • ... levels • NMO-IgG (anti-AQP4 ... AntiCRMP IgG, Anti-Hu
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... the underlying cause ... Seizures: Treat with AEDs ... until cause identified
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... neuropathy, transverse myelitis ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Clinical Features ... Erythematosus #Diagnosis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... renal failure Clinical ... at the time of diagnosis ... nodules; anterior/posterior ... MSK, heart (2-5%
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibodies (ANA) ANA or Anti-NucIear ... likely it will be clinically ... SLE), Sjogren's Syndrome ... , Myositis, Mixed ... #diagnosis #differential