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diagnosis differential management causes algorithm pharmacology pathophysiology treatment clinical table allergic classification comparison dermatology pulmonary antibiotics hematology immunology workup criticalcare
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE - Soluble antigen ... - Allergen-specific ... When the specific allergen ... Local and systemic anaphylaxis ... Pathophysiology #Allergy
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mediators: lgE - Antigen ... Form: Soluble antigen ... Mechanism of Action: Allergen-specific ... hours - Examples: Anaphylaxis ... reactions #types #allergy
Drug Treatment of Anaphylaxis and Allergic Reactions First-Line Therapy - Epinephrine - Oxygen -
Drug Treatment of Anaphylaxis ... and Allergic Reactions ... Prednisone #Anaphylaxis ... #Medications #Allergy
Pediatric Anaphylaxis Algorithm #Anaphylaxis #Algorithm #Pediatrics #Peds #Allergy
Pediatric Anaphylaxis ... Algorithm #Anaphylaxis ... Pediatrics #Peds #Allergy
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... Macrophage engulfs antigen ... -> Antigen presentation ... cells recognize antigen
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... conjunctivitis • Anaphylaxis
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Immunological Target: Antigen-Ab ... Hypersensitivity #Allergy ... #Allergic #Reactions
Management of Anaphylaxis - Interventions Epinephrine - Bolus, Infusion, Nebulized Posture O2 Fluids Albuterol H1-Antihistamines, H2-Antihistamines Glucocorticoids Additional Vasopressor Glucagon Sugammadex Methylene blue Tranexamic acid ECMO #anaphylaxis #management #treatment
Management of Anaphylaxis ... Tranexamic acid ECMO #anaphylaxis ... Interventions #allergy
Pharmacology: Anti-Allergic Therapy #Pharmacology #Mechanisms #Allergy #Antiallergic #AntiAllergen #Antihistamines #Leukotrienes
Pharmacology: Anti-Allergic ... Pharmacology #Mechanisms #Allergy
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... -> Antigen Exposure ... class II) process antigen ... Tissue edema #Allergic
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