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Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
against the antigen ... cell surface, and antigen-surface ... small antibody-antigen ... An allergic reaction ... #Allergic #Reactions
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Penicillin-induced drug reaction ... Immunological Target: Antigen-Ab ... Dermatitis (ie. reaction ... #Allergic #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... Macrophage engulfs antigen ... -> Antigen presentation ... cells recognize antigen
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... Acute transfusion reaction ... hypersensitivity #reactions ... #types #allergy
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Primary Reaction ... Secondary Reaction ... after the primary reaction
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE - Soluble antigen ... - Allergen-specific ... When the specific allergen ... Pathophysiology #Allergy ... #Diagnosis #Reactions
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
surfaces, forming an "antigen-surface ... antibody-mediated immune reaction ... Antigen binds receptor ... against either the antigen ... HypersensitivityReaction #Allergy
Allergic Reaction Classification Type 1 reaction: Acute anaphylactic reaction Type 2 reaction: Cytotoxic reaction Type 3 reaction: Immune complex Type
Allergic Reaction ... Type 2 reaction ... Type 3 reaction ... #Allergic #Reaction ... Classification #Types #allergy
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... reaction. ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen
Drug Treatment of Anaphylaxis and Allergic Reactions First-Line Therapy - Epinephrine - Oxygen -
Anaphylaxis and Allergic ... Reactions First-Line ... #Medications #Allergy
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