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diagnosis hematology management oncology reactions algorithm anemia aplastic classification cryofibrinogenemia dermatologic differential gpa granulomatosis hemophagocytic hlh isolated lymphohistiocytosis lymphoma neutropenia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Pruritis • Erythema nodosum ... genes and gene products ... Workup: • Full Blood ... marrow biopsy - if blood ... classification #hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Anticonvulsants • Antibiotics ... • Epstein-Barr Virus ... Gram Positive Bacteria ... #Hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Polyarteritis nodosa ... disease • Non-Hodgkin ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Blood products contain ... very rare), or bacterial ... - Bacterial ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Infections+++: Virus ... CMV, HHV8,...), Bacteria ... Hemopathies+++: Hodgkin ... treatment #summary #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Blood products contain ... very rare), or bacterial ... • Bacterial contamination ... diagnosis #management #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of fibrin split products ... which can plug blood ... • Fibrin split products ... cryoglobulins • Negative causes ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - β-lactam antibiotics ... • Epstein-Barr virus ... result from low blood ... Anemia #oncology #hematology
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