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management hematology differential neurology cardiology chronic cll leukemia lymphocytic rheumatology syndromes workup acidosis acute antiphospholipid aplastic apls barre bloodsmear borrelia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... Clinical Presentation ... Treatment: ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... 5) Symptoms of anemia ... 3) Monoclonal antibodies ... Lymphocytic #Leukemia #oncology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
enzymes ↑ • Mild anemia ... Detects both HIV antibody ... Phase: • The short ... HIV-1 or HIV-2 antibodies ... test) Treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
quantify renal injury ... EGPA) • Auto-antibodies ... : ANCA antibody, ... Anti-GBM antibody ... #management #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Direct muscle injury ... myopathy (IMNM) → Antibodies ... Risk of muscle injury ... IU/I • SAMS clinical
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Clinical ... • Weakness: Starts ... Guillain-Barre Diagnosis ... equina • GQ1b IgG Antibody ... #treatment #neurology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup Algorithm ... - 1 or more clinical ... Antiphospholipid #Syndrome ... #diagnosis #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and pernicious anemia ... Clinical Manifestations ... levels of GAD, an antibody ... Treatment: • ... #Management #treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology
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