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management differential hematology neurology acute algorithm anemia anticoagulation aplastic apls aps barre bloodsmear borrelia guidelines guillain guillainbarre hiv hypercoagulable microscopy
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... at least: • 1 clinical ... presence of 1 clinical ... to be present Treatment ... #Syndrome #APS
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... - 1 or more clinical ... #Syndrome #Hypercoagulable ... Workup #Algorithm #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
quantify renal injury ... EGPA) • Auto-antibodies ... : ANCA antibody, ... Anti-GBM antibody ... #management #treatment
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Detects both HIV antibody ... Phase: • The short ... HIV-1 or HIV-2 antibodies ... IgM-sensitive HIV-1 antibody ... test) Treatment
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Direct muscle injury ... myopathy (IMNM) → Antibodies ... Risk of muscle injury ... IU/I • SAMS clinical
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Clinical ... • Weakness: Starts ... Guillain-Barre Diagnosis ... equina • GQ1b IgG Antibody ... #treatment #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... Aplastic Anemia Clinical ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Presentation: Injury ... glycoprotein (MOG) antibody ... Antiamphiphysin antibodies ... Transverse Myelitis Treatment
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Syndrome: 3d of ... Specific organ injury ... LBRF can be diagnosed ... and convalescent antibodies ... microscopy #pathology #clinical
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... /EGPA • RA Diagnosis ... : • Clinical tests ... Anti-Matrilin-1 Ab ○ Antibodies ... affected tissue Treatment
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