89 results
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease

Autoimmune thyroid disease overlap syndrome
destruction by cell and antibody-mediated ... peroxidase (TPO) antibodies ... • TSH-receptor antibodies ... your balance of antibodies ... Endocrinology #Pathophysiology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... or Anti-NucIear Antibody ... refers to antibodies ... likely it will be clinically ... rheumatology #diagnosis #differential
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Pathogenesis and clinical ... a maladaptive antibody-mediated ... produce autoimmune antibodies ... entire complex -> Antibody ... Allergy #Immunology #pathophysiology
Clinical Manifestations and Diagnosis of Lyme Disease - Borreliosis
Erythema migrans
 - 3-32 days (median: 7-10 days)
Clinical Manifestations ... Diagnosis of Lyme Disease ... High specific IgG antibody ... Intrathecal specific antibody ... missing in early disease
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Pathogenesis and clinical ... Production of lgE Antibodies ... that secrete lgE-antibodies ... -> Allergen-antibody ... Allergy #Immunology #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... epidemiology of this disease ... history of the disease ... decline in maternal antibody ... Agammaglobulinemia #XLinked #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... - IgG or IgM antibody ... during hemolytic disease ... antigen - Antigen-antibody ... Classification #Pathophysiology
Alzheimer's Disease - Summary
 • Epidemiology
 • Pathophysiology
 • Risk Factors
 • Presentation
 • Diagnosis
 •
Alzheimer's Disease ... Epidemiology • Pathophysiology ... Treatment • Clinical ... #Alzheimers #Disease ... Summary #diagnosis #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
an autoimmune disease ... Diagnosis: • Based on clinical ... myasthenia usually • Starts ... - Improves clinical ... Gravis #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Purpura Anti-GBM antibodies ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis #differential