44 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... or Anti-NucIear Antibody ... context of other symptoms ... likely it will be clinically ... rheumatology #diagnosis #differential
Clinical Manifestations and Diagnosis of Lyme Disease - Borreliosis
Erythema migrans
 - 3-32 days (median: 7-10 days)
Clinical Manifestations ... Diagnosis of Lyme Disease ... High specific IgG antibody ... missing in early disease ... Diagnosis #Signs #Symptoms
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... history of the disease ... decline in maternal antibody ... immunity Signs/Symptoms ... Agammaglobulinemia #XLinked #pathophysiology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Viral Infection Clinical ... younger pts) Differential ... Donath-Landsteiner (IgG) antibodies
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... decreased reflexes Pathophysiology ... Residency @CMC_IM #Potts ... #Disease #Tuberculosis
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Pathogenesis and Clinical ... paresthetica • Symptoms ... intervertebral disc disease ... MeralgiaParesthetica #MSK #pathophysiology ... #differential #
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Detects both HIV antibody ... Phase: • The short ... HIV-1 or HIV-2 antibodies ... IgM-sensitive HIV-1 antibody ... ART to slow HIV disease
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... : ANCA antibody, ... Anti-GBM antibody ... or serologies + symptoms ... #diagnosis #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
an autoimmune disease ... Diagnosis: • Based on clinical ... myasthenia usually • Starts ... - Improves clinical ... Gravis #diagnosis #management
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... but elevated as disease ... • Antithyroid antibodies ... bile ducts Differential