18 results
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease

Autoimmune thyroid disease overlap syndrome
destruction by cell and antibody-mediated ... peroxidase (TPO) antibodies ... • TSH-receptor antibodies ... Hashitoxicosis #Endocrinology ... #Pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
a maladaptive antibody-mediated ... specific pre-formed antibodies ... produce autoimmune antibodies ... entire complex -> Antibody ... Allergy #Immunology #pathophysiology
Hypoglycemia Differential Diagnosis and Management Algorithm

Features of hypoglycemia:
 • Neurogenic: Tremor, Palpitations, Anxiety, Arousal, Sweating, Hunger,
Hypoglycemia Differential ... Glucose • Insulin Antibodies ... #Hypoglycemia #Differential ... Management #Algorithm #endocrinology
Hyperthyroidism - Differential Diagnosis Algorithm
High/Normal Radioiodine Uptake
 - Autoimmune Thyroid Disease:
    • Grave's
Hyperthyroidism - Differential ... anti-TSH Receptor Antibody ... #HighThyroid #Differential ... Diagnosis #Algorithm #endocrinology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Production of lgE Antibodies ... that secrete lgE-antibodies ... creating an allergen-antibody ... -> Allergen-antibody ... Allergy #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... - IgG or IgM antibody ... antigen - Antigen-antibody ... Classification #Pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
decline in maternal antibody ... immunoglobulin proteins (antibodies ... or undetectable antibodies ... Agammaglobulinemia #XLinked #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Purpura Anti-GBM antibodies ... Glomerulonephritis #Vasculitis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... or Anti-NucIear Antibody ... refers to antibodies ... #Antinuclear #Antibodies ... rheumatology #diagnosis #differential
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
antiphospholipid antibodies ... FVIII antibody ... antiphospholipid antibodies ... Causes #diagnosis #differential