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Hydroxocobalamin Pharmacology – Cyanide Antidote

By Dr. Kathryn Watson @Kat_Watson

#Hydroxocobalamin #Cyanide #Antidote #Toxicology #Management #Pharmacology
Hydroxocobalamin ... Pharmacology – Cyanide ... Antidote By ... #Cyanide #Antidote ... #Toxicology #Management
Table 3. Antidotes that may be used in cardiac arrest (The A to P of treatment
Antidotes that may ... used in cardiac arrest ... (The A to P of treatment ... #Management #Toxicology ... #Antidotes #Cardiac
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Treatment: 1 ... ) Hydroxocobalamin ... #Toxicity #Toxicology ... Pathophysiology #Management #Treatment
Alternative or ContingencyCountermeasures for Acetylcholinesterase Inhibiting Agents
A nerve agent event may deplete local stocks of @US_FDA-approved
US_FDA-approved antidotes ... approved as nerve antidotes ... #Management #Toxicology ... Acetylcholinesterase #Inhibitors #AchEI ... #Antidotes #Countermeasures
In addition to management of ABCs, exposure to nerve gases requires antidotes. There are 3 important
gases requires antidotes ... #Management #Toxicology ... #NerveAgents #Treatment
Medical Management of Riot-Control Agents AKA Tear Gas - 
Decontamination:
1) Remove clothing by cutting off, don't
Management: • No antidote ... TearGas #management #treatment ... #toxicology #diagnosis
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... (folinic acid) treatment ... Methotrexate #Leucovorin #Antidote ... #Toxicology #Toxicity