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management hematology neurology aflp aids alzheimersdisease biliary caudaequina central cholangitis cirrhosis clues dementia encephalopathy endocrinology excess fatty geriatrics gh growthhormone
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... Note: Surgical Emergency ... #MSK #pathophysiology ... #diagnosis #symptoms
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
(Wallenberg's syndrome ... Syndrome usually ... varying neurologic signs ... #differential # ... diagnosis #neurology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Pressure: • Headache ... Carpal Tunnel Syndrome ... Overproduction #diagnosis ... #signs #symptoms
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... = nonspecific (nausea ... abdominal pain, headache ... infiltration) Differential ... Liver #Pregnancy #hepatology
Emergent Causes of Headache and Associated Risk Factors Carbon monoxide poisoning - Breathing in enclosed or confined
Emergent Causes ... vasoconstriction syndrome ... #redflags #signs ... #symptoms #differential ... #emergency #diagnosis
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... vasoconstriction syndrome ... #signs #symptoms ... #clues #differential ... #diagnosis
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... Exertional Heat Stroke: EMERGENCY ... #diagnosis #causes
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
characterized by: • Headache ... Hypertension/Hypertensive emergency ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential
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