236 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... • Type II - Antigenic ... reaction against the antigen ... cell surface, and antigen-surface ... small antibody-antigen
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... Macrophage engulfs antigen ... -> Antigen presentation ... cells recognize antigen
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Definition: When antigens ... These antigens can ... either be self-antigens ... , or foreign antigens ... HypersensitivityReaction #Allergy
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Definition: Small antigen-antibody ... If self-antigens ... If bacterial antigens ... HypersensitivityReaction #Allergy
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mediators: lgE - Antigen ... Form: Soluble antigen ... Mechanism of Action: Allergen-specific ... complex - Antigen ... reactions #types #allergy
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Immunological Target: Antigen-Ab ... Hypersensitivity #Allergy ... #Allergic #Reactions
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE - Soluble antigen ... - Allergen-specific ... When the specific allergen ... IgM - Cell-bound antigen ... Pathophysiology #Allergy
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... -> Antigen Exposure ... class II) process antigen ... Tissue edema #Allergic
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
interaction of the allergen ... (antigen), antigen ... mucus production allergic
Group A Strep Pharyngitis, also known as  Strep Throat. 

In addition to symptomatic presentation, a
presentation, a rapid antigen ... true penicillin allergy ... with "penicillin allergy ... actually have a true allergy ... pharmacists - penicillin allergy