6 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
#hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #potassium ... #medications #druginduced
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... and sodium • Dosing ... of aspiration #Potassium ... #Hyperkalemia #medications ... pharmacology #table #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... • Recent IV potassium ... Medications 2. ... #hyperkalemia #differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... • Recent IV potassium ... Medications 2. ... #hyperkalemia #differential
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
Peripheral Edema - Differential ... Bilateral • Protein-losing ... insufficiency • Medications ... Peripheral #Edema #differential ... #PhysicalExam #Pathophysiology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypokalemic salt-losing ... Hypokalemia (renal potassium ... ratio 0.5%) Differential ... Supplement: • Potassium ... nephrology #management #pathophysiology