12 results
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Erythema nodosum • Immune ... Immunohistochemical studies (to differentiate ... through Ann Arbor criteria ... hematology #oncology #management
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... disease Rare causes ... cell lymphomas, Hodgkin ... malignancy - Immune ... hypereosinophilia #HE #Differential
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... Hemopathies+++: Hodgkin ... Others: Cellular immune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... inflammation • Pauci-immune ... reticularis Differential ... Nasopharyngeal carcinoma • Hodgkin ... disease • Non-Hodgkin
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
cells are the immune ... - Causes progressive ... : El Escorial criteria ... conditions listed in differential ... neurology #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... Diagnostic Criteria ... • Infectious causes ... Myelitis #diagnosis #management ... #neurology #differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Criteria for Diagnosis ... Resolution > 15 days Differentials ... Exanthematous Pustulosis Management ... dermatology #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
effects of SCC or Hodgkin ... muscles: “myasthenic crises ... life-threatening Differential ... Myasthenia Crises ... Gravis #diagnosis #management
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Septic Emboli Cause ... Marantic (NTBE) Differential ... -> TEE • Duke Criteria ... Treat underlying cause ... Endocarditis #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... specific diagnostic criteria ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management