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Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pure red cell aplasia ... Pure #RedCell #Aplasia ... Microscopy #Hematology #Clinical
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... mutations) • Immune Aplastic ... Anemia Clinical ... HIV • Immune Aplastic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Pure red cell aplasia
Clinical features of focal cortical brain lesions in a right-handed individual Frontal, either: Intellectual impairment, Personality
Clinical features ... left: Broca's aphasia ... Agraphia, Werneke's aphasia ... right: Dressing apraxia ... left: Limb apraxia
Causes of Aphasia - Differential Diagnosis Algorithm Fluent - Grammatically correct, but nonsensical, tangential. Phonemic & semantic
Causes of Aphasia ... , Global Aphasia ... , Broca's Aphasia ... Transcortical Aphasia ... #Aphasia #Neurology
Causes of Non-Fluent Aphasia - Differential Diagnosis Algorithm Non-Fluent - Agrammatic, hesitant, but substantive communication Impaired Repetition •
of Non-Fluent Aphasia ... Comprehension - Global Aphasia ... Transcortical Aphasia ... Transcortical Motor Aphasia ... #NonFluent #Aphasia
Stroke Territory Localization and Blood Vessel Supply ACA (Anterior Cerebral Artery) - Leg weakness/numbness MCA Superior Divison -
Divison - Broca Aphasia ... Division - Wernicke Aphasia ... numb - Global Aphasia ... arm/leg + global aphasia
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Pathogenesis and Clinical ... semantic memory • Aphasia ... incontinence, apraxia
Aphasia - Pathophysiology and Clinical Findings Broca's Aphasia - Expressive language impairment: non-Fluent - Sensory speech areas
Aphasia - Pathophysiology ... and Clinical Findings ... Broca's Aphasia ... repetition Wernicke's Aphasia ... sensory deficits #Aphasia
Clinical Features and Vascular Territories of Stroke Anterior circulation—anterior cerebral artery (ACA) - Contralateral leg weakness Anterior circulation—middle
Clinical Features ... loss, field cut, aphasia ... MCA) or neglect, apraxia
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