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diagnosis differential dermatology generalized leukemia pruritus systemic abnormal anemia aplastic chronic classification cll cushings disorders endocrinology enzymes eosinophil hepatology hypercortisolism
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Liver Function Tests ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #causes
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
algorithm. ... symptoms/signs ... urgent referral to secondary ... presence of metabolic syndrome ... #Hepatology #Liver
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Liver Function Tests ... Myelodisplastic syndrome ... #Pruritus #secondary ... #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... and petechiae Causes ... - Hepatitis, eosinophilic ... #hematology #diagnosis
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Diagnosis and Clinical ... , oral cavity) Caused ... dexamethasone suppression test ... Hypercortisolism #Diagnosis #signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Hepatomegaly • Skin ... diagnosis #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... tract, and often causes ... • Cogan Syndrome ... purpura: strong sign ... retinopathy Lab Tests
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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