14 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... exertion • Neurologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... Signs/Symptoms: ... numbness, decreased reflexes ... Pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... bladder and rectal reflex ... #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Pathogenesis and Clinical ... - pupillary reflex ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... course of the disease ... Increased Jaw Jerk reflex ... Lateral #Sclerosis #neurology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Pathogenesis and Clinical ... intervertebral disc disease ... gait, strength, reflexes ... MeralgiaParesthetica #MSK #pathophysiology ... #signs #symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... Behcet syndrome (Clinical ... inhibitors • Uveitis- Ophthalmology ... #management #signs
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... diffuse light reflex ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs