17 results
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
Blood cultures growing ... Infective Endocarditis ... #Endocarditis #PhysicalExam ... #clinical #photo ... #skin
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Clinically significant ... of peripheral blood ... cultures, including blood ... bacteremia • Abnormal ... neutrophil #WBC #CBC #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... nose chondritis, skin ... Abnormalities: macrocytic anemia ... including peripheral blood ... myeloid cells NEJM
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vibrio Vulnificus skin ... vulnificus part of normal ... hemochromatosis, hemolytic anemia ... #legs #clinical ... #photo
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... Idiopathic • Infections ... result from low blood ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... petechiae) • Frequent infections ... • Parvovirus infection ... cell types are abnormal ... Syndromes #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
deficiency - Abnormal ... : • Complete blood ... • Fecal occult blood ... cryoglobulins • Skin ... #physicalexam
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... Capnocytophaga canimorsus normal ... possible Patient's clinical ... #Rash #dermatology ... #clinical #photo
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cooled from the normal ... which can plug blood ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia