9 results
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
from the cerebral cortex ... may arise from disease ... may mimic an LMN disorder ... LMN syndromes are ... very different clinical
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... (AQP4-lgG disease ... Comorbid autoimmune disorders ... neurology #symptoms #signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... neurological lesion: Clinical ... • Symptoms and signs ... MCTD, Sjogren syndrome ... Loss of muscle (atrophy
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ulceration • Ocular ... white matter, spinal ... (Clinical Dx). ... diagnosis #management #signs
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... • Scarring, atrophy ... ) • Endocrine disorders ... Clinical Features
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... Diagnosis and Clinical ... head • Muscle atrophy ... • The adrenal cortex ... Hypercortisolism #Diagnosis #signs
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... Ocular- 50%: Ptosis ... test - Cogan sign ... - Peek sign ... stimulation - Single
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... impairment, Mood disorder ... stimulation Clinical ... Progressive MS (Spinal
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... Rheumatic pain Clinical ... skeleton-sacroiliac joint and spine ... osteoarticular and skin disease