13 results
Uveitis - Definition, Causes and SUN Classification

Inflammation of the iris, ciliary body, vitreous, retina and/or choroid
Incidence
Inflammation of the iris ... blindness, linked to macular ... , sarcoidosis, Behcet ... #Differential #Diagnosis ... Ophthalmology #Rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Alzheimer - 1st cause ... functions - Aphaso-apraxo-agnosia ... syndrome - Hippocampal ... (parkinsonian signs ... - 2nd cause after
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia ... pathophysiology #geriatrics #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... ulceration • Ocular ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... skin lesions, ocular ... Zoster flare, ocular ... #Inflammatory #Syndrome ... #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Ocular- 50%: Ptosis ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... #management #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... VASCULITIS: • Behçet ... purpura: strong sign ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... sites such as the collar ... #Rheumatology # ... diagnosis #management