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diagnosis differential classification disease geriatrics symptoms vasculitis alzheimersdisease behcet behcets dermatology gravis hematology immune inflammatory leukostasis lysis mncd myasthenia neurology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia ... geriatrics #diagnosis #signs
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
Alzheimer - 1st cause ... functions - Aphaso-apraxo-agnosia ... syndrome - Hippocampal ... (parkinsonian signs ... - 2nd cause after
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... skin lesions, ocular ... Zoster flare, ocular ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... Leukemia, Lymphoma Ocular ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... test - Cogan sign ... - Peek sign ... Myasthenia Crises ... Gravis #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ulcers, cutaneous, ocular ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... Rule out other causes ... sites such as the collar ... #Rheumatology # ... diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... ulcers, cutaneous, ocular ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
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