6 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia ... geriatrics #diagnosis #signs
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
functions - Aphaso-apraxo-agnosia ... syndrome - Hippocampal ... atrophy Lewy body dementia ... (parkinsonian signs ... Frontotemporal dementia
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... immunosuppressive meds • +/- Anticoagulation ... Behcets #disease #Syndrome ... #Treatment #management
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... present Treatment (EULAR ... Antiphospholipid #Syndrome ... APS #diagnosis #management ... #anticoagulation
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... spondyloarthritis • Ocular ... Leukemia, Lymphoma Ocular ... #diagnosis #management ... #signs #symptoms
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... Ocular- 50%: Ptosis ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management