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management oncology rheumatology chronic cll leukemia lymphocytic agglutinin cold cvid dermatologic disease erythematosus gap globulin gpa granulomatosis hand hemeonc hemolytic
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Nodules • Lymphoid ... hemolytic anemia ... DDX - Other causes ... #immunology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Overview: • Most common ... immunophenotype Clinical ... Infection due to hypogammaglobulinemia ... to large cell lymphoma ... Leukemia #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... ingestion • B symptoms ... (NSHL) - (most common ... #diagnosis #classification ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... Orange or Hep C Clinical ... with no early symptoms ... • Neutropenia, anemia ... workup #oncology #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... - most common presentation ... younger pts) Differential ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... Kidney disease common
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
diffuse palpable rash ... Diagnosis? ... Differential for ... Hand #skinrash #dermatology ... #clinical #photo
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... Comment on type ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... : • Gottron rash ... , and lymphoma ... , and lymphoma ... statins - probably caused
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