9 results
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Approach to Acid ... Base Disorders ... - Evaluation and ... Differential Diagnosis ... #Evaluation #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... - Bone marrow evaluation ... #Differential #
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... : • Valvular disorders ... iron deficiency anemia ... Myeloproliferative disorders ... Vasoplegia • Sepsis
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... (AG) = {Na - (Cl ... Renal failure (uremia ... #AcidBase #disorders ... ABG #bloodgas #Acid
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... PRIS), Valproic Acid ... Malaria, Late Sepsis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... vitamin B12 or folic acid ... Workup: • Complete ... blood count with differential
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... phlebotomy/ blood work ... during clinical evaluations ... • Iron, folic acid ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... ) • Endocrine disorders ... , APLA, PAC • Aseptic ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential