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diagnosis hematology management oncology lymphoma activation chronic classification cll comparison erythematosus hemophagocytic hlh knee lesions leukemia lupus lymphocytic lymphohistiocytosis macrophage
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... • Aneurysmal bone ... #Differential # ... #peds #pediatrics ... #msk #lesions #adult
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Epidemiology: young adults ... Autoimmune diseases • Clinical ... Noncontiguous spread • Clinical ... involvement Differential ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... classification #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... Orange or Hep C Clinical ... Warm AIHA • Bone ... PML leukemia, Hodgkin ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... /ml, ↑ LDH • Bone ... Hemopathies+++: Hodgkin ... diseases: SLE+++, Adult-onset ... treatment #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... hemophagocytosis in the bone ... CD163 staining of bone ... is found in the bone ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... rheumatoid arthritis, adult-onset ... , APLA, PAC • Aseptic ... cyclophosphamide) • Hodgkin
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