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Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Bugs: - Fungus (aspergillosis ... Glucocorticoids Pugs (Allergies ... ): - Allergic ... Rhinitis - Allergic
On the left we see a chest film with a typical finger-in-glove shadow.
The HRCT shows focal
eosinophilia) typical for Allergic ... bronchopulmonary aspergillosis ... CTChest #ABPA #Allergic ... #Aspergillosis
ABPA Working Group Criteria

#ABPA #allergic #bronchopulmonary #aspergillosis #diagnosis #Criteria
Criteria #ABPA #allergic ... bronchopulmonary #aspergillosis
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
infection - Allergic ... + T cells) - Allergic ... bronchopulmonary aspergillosis
Stages of ABPA
I - Acute Phase
II - Remission
III - Exacerbation
IV - Glucocorticoid-Dependent ABPA
V - End-Stage (fibrotic)
classification #allergic ... bronchopulmonary #aspergillosis
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
Allergic Bronchopulmonary ... Aspergillosis ( ... @PulmPEEPs #Allergic ... Bronchopulmonary #Aspergillosis
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
; Hx of asthma/allergies ... loss, malaise • Allergic ... Bronchopulmonary Aspergillosis
Tree-in-bud almost always indicates the presence of:
Endobronchial spread of infection (TB, MAC, any bacterial bronchopneumonia)
Airway disease
mucus retention (allergic ... bronchopulmonary aspergillosis
Bronchiectasis - Permanent dilation of an airway
WHAT CAN YOU SEE ON CT?
1) Lack of tapering of
NTM, Fungal) 4) Allergic ... Bronchopulmonary Aspergillosis
Mucoid impaction
Mucus plugs or mucoid impaction can mimick the appearance of lung nodules or a mass.
Sometimes
fibrosis (CF) and allergic ... bronchopulmonary aspergillosis