11 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Acute Thiamine (B1 ... Diagnosis - Caine ... dysfunction and gait ... ataxia is only ... #Deficiency #diagnosis
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
- Diagnosis and ... Management Diagnosis ... dysfunction (e.g. gait ... ataxia - usually ... #Diagnosis #Management
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... of confusion, ataxia ... (broad-based gait ... Korsakoff #Syndrome #diagnosis ... #comparison #neurology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... Haemolytic anaemia, ataxia ... • Thiamine B1 ... #differential # ... diagnosis #signs
Causes of Gait Disturbance - Differential Diagnosis Algorithm
Sporadic
 • Vascular
 • Infection
 • Toxic
 • Nutrition
Causes of Gait Disturbance ... - Differential ... Diagnosis Algorithm ... #Disturbance #Differential ... #Diagnosis #Algorithm
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... mevalonate kinase deficiency ... #management #treatment ... #rheumatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
a storage pool deficiency ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
effusions, weight gain ... opacities • Diagnosis ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) in hematologic ... BAL GM does not differentiate ... following HSCT; with GIT ... Galactomannan #diagnosis ... #comparison
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
blindness, or gait ... ataxia • Papillomavirus ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management