8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... Ferritin >500 ng/mL ... #diagnosis #management ... #treatment #hematology
Positive Lachman's Test

The Lachman test is a clinical test used to diagnose injury of the anterior
test used to diagnose ... The knee is flexed ... The examiner should ... #Positive #Video ... #Knee
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... Assessment • Clinical ... #diagnosis #management ... treatment #summary #rheumatology
Demonstration of the Lachman Test for assess for ACL Injury - Normal Exam

Demonstration by Dan Smith,
test used to diagnose ... The knee is flexed ... The examiner should ... #Normal #Video ... #Knee
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
haemophagocytic lymphohistiocytosis ... 5000 to 10,000 ng/mL ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... Anterior circulation: MCA ... syndrome, ADEM, Acute toxic ... count in the CSF should ... #management #neurology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
, and back and shoulders ... dorsal part of the MCP ... auricular papules Clinical ... Dermatomyositis #diagnosis ... #management #rheumatology