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diagnosis differential hepatology management nephrology liver causes injury chronic gastroenterology hepatitis medications rheumatology workup acidosis aclf aki aniongap bariatric bypass
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Kidney Failure ... Infections Alcohol-Associated
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... LC deposition disease ... • Hematologic ... malignancies Treatment ... #Kidney #Injury
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... Neoplastic / Hematologic ... Obstructive Pulmonary Disease ... Neurologic • ... Alcohol) • Drug
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Torsemide) • Acute ... disease • Liddle ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... cardiac muscle, kidneys ... differential #diagnosis #algorithm ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... dechallenge • Acute
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... : - Acute kidney ... - Concomitant diseases ... - Multiorgan failure ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure ( ... of cholestatic disease ... ALT Ratios: • Alcoholic ... liver disease: ... #differential #Hepatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... maintenance with GCs ... #rheumatology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Ketoacidosis: Diabetic, Alcoholic ... oxoproline) • Renal failure ... (acute and chronic ... Chronic progressive kidney ... disease Ill.
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