250 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... Sensitization" to Allergen ... complexes bind ... conjunctivitis • Anaphylaxis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... lgE antibodies bind ... When the specific allergen ... Local and systemic anaphylaxis ... Pathophysiology #Allergy
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... hours - Examples: Anaphylaxis ... lgM antibodies bind ... reactions #types #allergy
Drug Treatment of Anaphylaxis and Allergic Reactions
First-Line Therapy 
 - Epinephrine 
 - Oxygen 
 -
Drug Treatment of Anaphylaxis ... and Allergic Reactions ... Prednisone #Anaphylaxis ... #Medications #Allergy
Pediatric Anaphylaxis Algorithm 

#Anaphylaxis #Algorithm #Pediatrics #Peds #Allergy
Pediatric Anaphylaxis ... Algorithm #Anaphylaxis ... Pediatrics #Peds #Allergy
Management of Anaphylaxis - Interventions
Epinephrine - Bolus, Infusion, Nebulized
Posture
O2
Fluids
Albuterol 
H1-Antihistamines, H2-Antihistamines
Glucocorticoids
Additional Vasopressor
Glucagon
Sugammadex
Methylene blue
Tranexamic acid
ECMO

#anaphylaxis #management #treatment
Management of Anaphylaxis ... Tranexamic acid ECMO #anaphylaxis ... Interventions #allergy
Pharmacology: Anti-Allergic Therapy

#Pharmacology #Mechanisms #Allergy #Antiallergic #AntiAllergen #Antihistamines #Leukotrienes
Pharmacology: Anti-Allergic ... Pharmacology #Mechanisms #Allergy
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Immunological Target: Allergen ... Hypersensitivity #Allergy ... #Allergic #Reactions
Diagnostic Criteria of Anaphylaxis (from TheCribsiders Pediatric Podcast) #diagnosis #peds #allergy
Diagnostic Criteria of Anaphylaxis ... diagnosis #peds #allergy
Algorithm for Suspected Penicillin Allergy in Patients Undergoing Surgery 

• Cephalosporins may be prescribed to patients
Suspected Penicillin Allergy ... reported penicillin allergy ... true penicillin allergy ... 100,000 risk of anaphylaxis ... #Penicillin #Allergy